Clayton Christensen's book, "The Innovator's Prescription: A Disruptive Solution for Healtch Care", is a must-read for anybody interested in understanding how the complicated healthcare system can and will be disrupted. No need to rehash a review here, when there are several accurate ones on Amazon.
An important take-away from the book: there can and will be innovative disruption of the American healthcare system as long as the morass of government regulations don't get in the way. This is an important point, as healthcare is highly regulated in its current state. Innovation requires freedom to experiment, struggle, fail, and evolve.